알레르기 비염, 이제 알레그라^®로 극복하고 자유로운 일상을 되찾으세요!

1. Van Cauwenberge et al. Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg. Clin Exp Allergy. 2000.30(6);891-899

2. Mark E et al. Efficacy and tolerability of 2nd and 3rd gen antihistamines. ANNALS OF ALLERGY, ASTHMA & IMMUNOL. 2010.104;518–522

3. Fein MN et al. CSACI position statement_Newer generation H1-antihistamines (3rd generation) are safer than first-generation H1-antihistamines. Allergy Asthma Clin Immunol. 2019.15(61);1-6

4. Anne K et al. Second-and third-generation antihistamines. DERMATOLOGIC THERAPY. 2000.13;327–336

5. Thomas B et al. Next generation antihistamines therapeutic rationale accomplishments and advances. Expert Opinion on Investigational Drugs. 2002.11(6);807-817

6. Day J H et al. Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride. Ann Allergy Asthma Immunol. 1997.79;533-540

7. Smith SM et al. Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders. Expert Opinion on Drug Metabolism & Toxicology. 2009.5(7);813-822

8. Peter H et al. Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine and cetirizine in seasonal AR. J ALLERGY CLIN IMMUNOL. 1999.104(5);927-933

9. 2023 소비자가 뽑은 올해의 브랜드대상, 2년 연속 수상 (알레르기비염 치료제 부문) 사단법인 한국방송신문연합회 주관

10. Brożek JL et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. J ALLERGY CLIN IMMUNOL. 2017.140(4);950-958

[Study Design¹] This was a multinational, multicentre, double-blind, parallel group, randomized, placebo-controlled study. Following a placebo run-in phase of 3±7 days (the baseline period), patients with SAR were randomized to receive one capsule of either fexofenadine HCl 120mg(n=232), loratadine 10mg(n=228), or placebo(n=225), once each morning for 14 days. The primary efficacy parameter was the change in the mean 24-h reflective TSS during the double-blind treatment period from that during the baseline period.

[Study Design⁶] This study was of a randomized, placebo-controlled, double-blind, parallel design. The purpose of this study was to characterize the time to onset of clinically important relief of symptoms of allergic rhinitis in subjects taking single doses of either 60 mg or 120 mg fexofenadine HCl, or placebo, after exposure to ragweed pollen in a controlled environment. Other objectives were to assess the efficacy and safety of single doses of fexofenadine HCl.

[Study Design⁸] A multicenter, double-blind, parallel-group, placebo-controlled trial compared the efficacy and safety of fexofenadine HCl (120 and 180 mg administered once daily) and cetirizine (10 mg once daily) in the treatment of seasonal allergic rhinitis. The primary efficacy variable was the change in mean 24-hour reflective TSS during the treatment period in relation to the single blind placebo lead-in phase.